Open Source Lab Equipment
Lack of cost-effective diagnostics is a major hurdle in the global fight against infectious disease, especially in low resource settings. This leaves our world in a highly vulnerable position with therapeutic drugs being either overused, leading to drug resistant strains or not accessible to people who actually need these treatments. Local context such as high cost, lack of trained personnel or low throughput of many available diagnostics tests plays a detrimental role on quality of delivered health-care.
To help solve these issues, the WoIDMo is developing low cost and high quality open source lab tools.
Mini Hematology Lab
Manual microscopy has served as a bedrock for diagnosing diseases such as Malaria, and direct visual identification of parasites remains the gold standard for numerous diseases. However, this comes at the cost of tedious labor and human errors. Human fatigue has been identified as a crucial factor in reduced efficiency in microscopy based diagnostics. The same technological advancements that will one day lead to self-driving cars is currently mature enough to take over this task.
Based on the openflexure robotic microscope, we are developing a low-cost 3D printable autonomous platform capable of counting blood cell types and detecting parasite infections through the application of machine-learning. The device allows screening of more than 1.5 million red blood cells per minute for infections, which is 120 times faster compared to traditional manual microscopy. The cost of constructing the mini hematology lab is expected to be around 300 USD.
Sources and instructions to construct the mini hematology lab are available on Github (in progress)
- Red blood cell count (RBC)
- White blood cell count (WBC)
- Differential white blood cell count
- Platelet count
- Parasite detection (eg Malaria)
- Battery powered (USB)
- Low cost
ELISA Plate Reader
Plate readers are instruments which are used with ELISA antibody tests as a diagnostic tool in hospitals and labs around the world. HIV, hepatitis and other viral diseases are diagnosed this way.
Cost of constructing the plate reader is expected to be below 150 USD and can be entirely 3D printed.
Sources and instructions to construct the ELISA plate reader will be available on Github (soon)
We cannot do this without your help
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