Tuberculosis – United States

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A surge in Tuberculosis cases across the US is linked to bone grafts individuals have been receiving.

The source of the infection is the bone grafts made by Aziyo Biologics Inc.

No specific number of infected patients was mentioned, but 8 patients died after procedures (the cause of death is still being investigated).

All patients who received these grafts have been notified.

Photo: Mycobacterium tuberculosis electron micrograph.

About one quarter of the world’s population has a tuberculosis infection, which means people have been infected but are not (yet) ill with the disease and cannot transmit it.

When a person develops active tuberculosis, the symptoms (such as cough, fever, night sweats, or weight loss) may be mild for many months. This can lead to delays in seeking care, and results in transmission of the bacteria to others. People with active tuberculosis can infect 5 to 15 other people through close contact over the course of a year.

The largest numbers of new tuberculosis cases occurred in South-East Asia, followed by Africa and the Western Pacific. In 2019, eight countries accounted for two thirds of the new tuberculosis cases: India, Indonesia, China, Philippines, Pakistan, Nigeria, Bangladesh and South Africa.

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